MelMarT-II: Melanoma Margins Trial-II - A Phase III, Multi-centre Randomised Controlled Trial Investigating 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
Patients with a primary invasive melanoma are recommended to undergo excision of the primary lesion with a wide margin. There is evidence that less radical margins of excision may be just as safe. This is a randomised controlled trial of 1 cm versus 2 cm margin of excision of the primary lesion for adult patients with stage II primary invasive cutaneous melanomas (AJCC 8th edition) to determine differences in disease-free survival. A reduction in [...]
Locations: Royal Preston Hospital (PI: Mr Richard Wain), Imperial College Healthcare NHS Trust (PI: Jonathan Dunne), Royal Cornwall Hospital (PI: Polly King), Hull University Teaching Hospitals NHS Trust (PI: Paolo Matteucci), The Christie NHS Foundation Trust (PI: Deemesh Oudit), Cambridge University Hospitals NHS Trust (PI: Amit Roshan and Amer Durrani), The Royal Marsden NHS Foundation Trust (PI: Myles Smith), Oxford University Hospitals NHS Foundation Trust (PI: Oliver Cassell), Guys and St Thomas' NHS Foundation Trust (PI: Jenny Geh), Nottingham University Hospitals NHS Trust (PI: Jonathan Pollock), North Bristol NHS Trust (PI: Ewan Wilson), Norfolk and Norwich University Hospital (PI: Prof Marc Moncrieff), The Leeds Teaching Hospitals NHS Trust (PI: Howard Peach), St George's University Hospitals NHS Foundation Trust (PI: Joy Odili), South Tees Hospitals NHS Foundation Trust of The James Cook University Hospital (PI: Oliver Bassett), St Helen's & Knowsley Hospitals Trust (PI: Prof Rowan Pritchard Jones), Royal Free London NHS Foundation Trust (PI: Stephen Hamilton), University Hospitals Birmingham NHS Foundation Trust (PI: Dr Agustin Martin-Clavijo), Mid and South Essex NHS Trust (PI: Professor Peter Dziewulski)