Clinical Research

Melanoma Focus is proud to be a charity that is committed to commission, fund, support and promote research into the wide field of melanoma for patient and public benefit.

We regularly invite applications from UK melanoma researchers. Thanks to kind donations, we have funded investigators who work as melanoma clinicians, advanced non-medical practitioners, scientists, pathologists, nurses and health economists. Our Medical Advisory Group evaluates the proposals and makes recommendations for the research awards.

A call for research applications is currently open. Scroll down to learn more about the opportunity and how to apply.

Previous studies have addressed complex scientific questions – such as a study looking at how changes in proteins in the skin can predict the risk of melanoma metastasising – and others are aimed at improving public knowledge of melanoma, its risks and prevention, as well as observational studies looking at different aspects of care to better understanding patient well-being and holistic care for melanoma patients.

Melanoma researcher

Melanoma Focus is an NIHR RDN Non-commercial Partner. This means the studies that we fund may be eligible to access the NIHR Study Support Service which is provided by the NIHR Research Delivery Network within the NHS, and the wider public health and social care environment, across England. Read the full policy here.

Application for Research Funding 2026

We are delighted to invite research proposals for patient and public benefit from clinicians/scientists/nurses/AHPs in the field of melanoma. Potential funding is up to £20,000.*

*higher requests, will be considered if appropriately justified.

Proposal submissions are now closed for 2026. 

 

 

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Current Research Projects 

See the research projects that Melanoma Focus is currently funding through donations  

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Past Funded Projects 

See the previous melanoma research studies that have been completed 

Melanoma Clinical Research Community News 

Fraudulent Participation in Online Qualitative Studies: Practical Recommendations on an Emerging Phenomenon – November 2024

 

A paper has been published exploring the fraudulent participation in online qualitative studies. The paper defines fraudulent participation as participation in research by individuals who, for one reason or another, intentionally provide false responses. Qualitative studies are at an increased risk of fraudulent participation when online recruitment and participation are used, and monetary incentives offered. However, validated guidance on how to prevent fraudulent participation is currently lacking, even though it threatens data quality and subsequent evidence-based practice.

This paper offers a critical reflection on fraudulent participation and develops the Prevent FRaudulent Online STudy participation (P-FROST) recommendations to provide advice on the following (1) Study set-up (including team members and study design), (2) Monetary incentives and recruitment, (3) Data collection (screening and interview considerations), and (4) Analysis, reporting, and support.

Read the full open access paper here.

OPTIC STUDY

Closure of the UK National Cancer Research Institute & Formation of the UK Skin Cancer Clinical Trial Group (UKSCCTG) supported by Melanoma Focus – September 2023

 

In June 2023, the UK National Cancer Research Institute (NCRI) announced its sudden closure after 22 years supporting and co-ordinating academic clinical cancer research across the UK – impacting all research groups, including the NCRI Skin Group. It is not immediately clear that another national organisation will pick up the mantle to design, develop and co-ordinate clinical cancer research in the UK. Read the NCRI closure announcement here.

The NCRI Skin Group had only recently published their Strategic Priorities, resulting from a delphi process and wide stakeholder engagement over a number of priority setting sessions. Read the NCRI Skin Group Strategic Priorities here.

Prof Rowan Pritchard-Jones (Chair, NCRI Skin Group) and Dr Brent O’Carrigan (Deputy Chair, NCRI Skin Group) have been approached by many members of the skin cancer research community who are enthusiastic to continue supporting academic clinical skin cancer research.

As an interim measure, they would like to convene stakeholders in UK academic skin cancer research (clinicians, researchers, scientists, patient advocates, funders and others) to come together and maintain cohesion in the community.

A proposed structure of this UK Skin Cancer Clinical Trial Group (UKSCCTG) would comprise of an Executive group and 3 working groups; Melanoma – early stage (including neoadjuvant therapy), Melanoma – metastatic, and, Non-melanoma skin cancers.

The Melanoma Focus Trustees have agreed that we will provide administrative support to allow the work to continue – including on both melanoma and non-melanoma skin cancer.

Melanoma TrialFinder Launches-May 2022

 

Melanoma Focus is committed to increasing the knowledge and understanding of current UK melanoma research. Our searchable UK Melanoma TrialFinder supports both professionals and patients; our aim being that meaningful discussions may occur between the medical team and patients about potential clinical trial opportunities.

The lay version of the Melanoma TrialFinder

The Melanoma TrialFinder for professionals

The Future of UK Clinical Research Delivery-May 2022

 

Our ongoing commitment to research at Melanoma Focus is further validated by a recent policy paper released by the UK Government Department of Health and Social care. The paper calls for the need to focus on Clinical Research in all areas.
The policy paper, called Saving and Improving Lives: The Future of UK Clinical Research Delivery was released in March 2021 and defines the vision for the future of clinical research in one of its opening statements:

“Clinical research is the single most important way in which we improve our healthcare – by identifying the best means to prevent, diagnose and treat conditions. So, we need to bolster delivery of innovative research across all phases, all conditions and right across the UK……

….And research extends beyond clinical trials for new medicines to cover a range of activities – from a study into a new approach to radiation therapy, to work to explore how a particular disease could be prevented, or even an investigation to help mitigate the side effects of a new treatment.

melanoma researcher

Clinical research is all around us and helps to improve the quality of healthcare patients receive. Crucially, these benefits are felt by everyone, not just those participating in research. For example, data shows NHS trusts that are highly research active have better outcomes for patients across their services.”

Read the full policy paper here.